BDBM346076 US10202370, Example 115::[1-Ethyl-6-methyl-2- (3-trifluoromethoxy- phenyl)-1H- benzoimidazol-5-yl]- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: CCn1c(nc2cc(Nc3nc(cs3)-c3cccnc3)c(C)cc12)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=OOZQDZSJBDCIIL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346076 (US10202370, Example 115 | [1-Ethyl-6-methyl-2- (3-...) Show SMILES CCn1c(nc2cc(Nc3nc(cs3)-c3cccnc3)c(C)cc12)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C25H20F3N5OS/c1-3-33-22-10-15(2)19(31-24-32-21(14-35-24)17-7-5-9-29-13-17)12-20(22)30-23(33)16-6-4-8-18(11-16)34-25(26,27)28/h4-14H,3H2,1-2H3,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair