BDBM346104 US10202370, Example 150::[2-(3-Isopropyl- phenyl)-6-methyl- 1H-benzoimidazol-5- yl]-(4-pyridin-4-yl- thiazol-2-yl)-amine

SMILES: CC(C)c1cccc(c1)-c1nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc2[nH]1

InChI Key: InChIKey=UMDSKRLTGOKFSR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346104 (US10202370, Example 150 | [2-(3-Isopropyl- phenyl)...) Show SMILES CC(C)c1cccc(c1)-c1nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc2[nH]1 Show InChI InChI=1S/C25H23N5S/c1-15(2)18-5-4-6-19(12-18)24-27-21-11-16(3)20(13-22(21)28-24)29-25-30-23(14-31-25)17-7-9-26-10-8-17/h4-15H,1-3H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair