BDBM350836 US9795602, Compound 28
SMILES: Oc1c2C(=O)N[C@H]3CCC[C@H]3n2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
InChI Key: InChIKey=QHTBWYDFKKHSRV-UONOGXRCSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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POU domain, class 2, transcription factor 2 (Homo sapiens (Human)) | BDBM350836 (US9795602, Compound 28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GILEAD SCIENCES, INC. US Patent | Assay Description The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an... | US Patent US9795602 (2017) BindingDB Entry DOI: 10.7270/Q2K35WTB | |||||||||||
More data for this Ligand-Target Pair |