BDBM352410 5′-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-2′-fluoro-2-methoxy-N-methylbiphenyl-4-carboxamide::US9802945, 21

SMILES: CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1CO)C(=O)NC

InChI Key: InChIKey=DLHAQCPCZSRYJC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM352410 (5′-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)...) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1CO)C(=O)NC Show InChI InChI=1S/C22H20FN5O2/c1-3-28-12-25-20-18(10-26-27-21(20)28)13-5-7-19(23)17(9-13)16-6-4-14(22(30)24-2)8-15(16)11-29/h4-10,12,29H,3,11H2,1-2H3,(H,24,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US9802945 (2017) BindingDB Entry DOI: 10.7270/Q2NP26JT
					More data for this Ligand-Target Pair