Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-2' and Ligand = 'BDBM352410'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM352410 (5′-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)...) Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1CO)C(=O)NC Show InChI InChI=1S/C22H20FN5O2/c1-3-28-12-25-20-18(10-26-27-21(20)28)13-5-7-19(23)17(9-13)16-6-4-14(22(30)24-2)8-15(16)11-29/h4-10,12,29H,3,11H2,1-2H3,(H,24,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US9802945 (2017) BindingDB Entry DOI: 10.7270/Q2NP26JT
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