BDBM354711 Preparation of (2R,5S)-3-(3-methyl-4-nitrophenyl)-2-(trifluoromethyl)oxazolidine-5-carboxylic acid::US9809583, Example 24
SMILES: O[C@@H]([C@@H]1CN([C@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(F)(F)F
InChI Key: InChIKey=CODCZUURZSYJCY-GARJFASQSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (Chlorocebus sabaeus (Green monkey) (Cercopithecus ...) | BDBM354711 (Preparation of (2R,5S)-3-(3-methyl-4-nitrophenyl)-...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
DONG-A ST CO., LTD. US Patent | Assay Description In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ... | US Patent US9809583 (2017) BindingDB Entry DOI: 10.7270/Q2C82CGC | |||||||||||
More data for this Ligand-Target Pair |