BDBM35910 flufenamic acid analogue, 36
SMILES: OC(=O)c1ccccc1Nc1cccc(OCc2ccccc2)c1
InChI Key: InChIKey=XETVGERWYQAJOQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen Receptor (Homo sapiens (Human)) | BDBM35910 (flufenamic acid analogue, 36) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | 7.2 | 23 |
St. Jude Research Hospital | Assay Description AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2... | ACS Chem Biol 4: 834-43 (2009) Article DOI: 10.1021/cb900143a BindingDB Entry DOI: 10.7270/Q2V986DC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM35910 (flufenamic acid analogue, 36) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de S£o Carlos Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin L expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by fluorometric analysis | Eur J Med Chem 54: 10-21 (2012) Article DOI: 10.1016/j.ejmech.2012.04.002 BindingDB Entry DOI: 10.7270/Q22J6CW7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin L2 (Homo sapiens (Human)) | BDBM35910 (flufenamic acid analogue, 36) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal de S£o Carlos Curated by ChEMBL | Assay Description Inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by fluorometric analysis | Eur J Med Chem 54: 10-21 (2012) Article DOI: 10.1016/j.ejmech.2012.04.002 BindingDB Entry DOI: 10.7270/Q22J6CW7 | |||||||||||
More data for this Ligand-Target Pair |