BDBM36488 CO22

SMILES: CC(C)c1cc(Oc2c(C)cc(Cc3[nH]c(=O)[nH]c3O)cc2C)ccc1O

InChI Key: InChIKey=ZZFTXXUUQNBOGX-UHFFFAOYSA-N

Data: 2 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM36488 (CO22) Show SMILES CC(C)c1cc(Oc2c(C)cc(Cc3[nH]c(=O)[nH]c3O)cc2C)ccc1O Show InChI InChI=1S/C21H24N2O4/c1-11(2)16-10-15(5-6-18(16)24)27-19-12(3)7-14(8-13(19)4)9-17-20(25)23-21(26)22-17/h5-8,10-11,24-25H,9H2,1-4H3,(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco					Assay Description Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.				ACS Chem Biol 1: 585-93 (2006) Article DOI: 10.1021/cb600311v BindingDB Entry DOI: 10.7270/Q23N21R4
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM36488 (CO22) Show SMILES CC(C)c1cc(Oc2c(C)cc(Cc3[nH]c(=O)[nH]c3O)cc2C)ccc1O Show InChI InChI=1S/C21H24N2O4/c1-11(2)16-10-15(5-6-18(16)24)27-19-12(3)7-14(8-13(19)4)9-17-20(25)23-21(26)22-17/h5-8,10-11,24-25H,9H2,1-4H3,(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.87E+3	n/a	n/a	n/a	n/a
University of California-San Francisco					Assay Description TRE-driven dual-luciferase reporter assay in human bone osteosarcoma epithelial (U2OS) cell line.				ACS Chem Biol 1: 585-93 (2006) Article DOI: 10.1021/cb600311v BindingDB Entry DOI: 10.7270/Q23N21R4
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM36488 (CO22) Show SMILES CC(C)c1cc(Oc2c(C)cc(Cc3[nH]c(=O)[nH]c3O)cc2C)ccc1O Show InChI InChI=1S/C21H24N2O4/c1-11(2)16-10-15(5-6-18(16)24)27-19-12(3)7-14(8-13(19)4)9-17-20(25)23-21(26)22-17/h5-8,10-11,24-25H,9H2,1-4H3,(H2,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
University of California-San Francisco					Assay Description Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.				ACS Chem Biol 1: 585-93 (2006) Article DOI: 10.1021/cb600311v BindingDB Entry DOI: 10.7270/Q23N21R4
					More data for this Ligand-Target Pair