null

SMILES: O[C@H]([C@@H](O)[C@@H](OCc1c(F)cccc1F)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)[C@@H](OCc1c(F)cccc1F)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key: InChIKey=YHWGARGFNUGEHK-JQFCFGFHSA-N

PDB links: 9 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM365 ((2R,3R,4R,5R)-2,5-bis[(2,6-difluorophenyl)methoxy]...) Show SMILES O[C@H]([C@@H](O)[C@@H](OCc1c(F)cccc1F)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)[C@@H](OCc1c(F)cccc1F)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |r| Show InChI InChI=1S/C38H36F4N2O8/c39-25-11-5-12-26(40)23(25)17-51-35(37(49)43-31-21-9-3-1-7-19(21)15-29(31)45)33(47)34(48)36(52-18-24-27(41)13-6-14-28(24)42)38(50)44-32-22-10-4-2-8-20(22)16-30(32)46/h1-14,29-36,45-48H,15-18H2,(H,43,49)(H,44,50)/t29-,30-,31+,32+,33-,34-,35-,36-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.64	-12.2	n/a	n/a	n/a	n/a	n/a	5.0	30
Linkoping University					Assay Description A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...				J Med Chem 44: 3083-91 (2001) Article DOI: 10.1021/jm001134q BindingDB Entry DOI: 10.7270/Q2DZ06GR
					More data for this Ligand-Target Pair