BDBM367210 2-oxo-7-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide::US10226452, Example 27

SMILES: O=C(NCCCCc1ccccc1)n1c2cccc(-c3ccccc3)c2oc1=O

InChI Key: InChIKey=UAGLATGVJCLIQU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid ceramidase (Homo sapiens (Human))	BDBM367210 (2-oxo-7-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole...) Show SMILES O=C(NCCCCc1ccccc1)n1c2cccc(-c3ccccc3)c2oc1=O Show InChI InChI=1S/C24H22N2O3/c27-23(25-17-8-7-12-18-10-3-1-4-11-18)26-21-16-9-15-20(22(21)29-24(26)28)19-13-5-2-6-14-19/h1-6,9-11,13-16H,7-8,12,17H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of recombinant human acid ceramidase expressed in HEK293 cells using N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)-4-(2-oxochromen-7-yl)-oxybutyl...				J Med Chem 58: 9258-72 (2015) Article DOI: 10.1021/acs.jmedchem.5b01188 BindingDB Entry DOI: 10.7270/Q2CF9T36
					More data for this Ligand-Target Pair
Acid ceramidase (Homo sapiens (Human))	BDBM367210 (2-oxo-7-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole...) Show SMILES O=C(NCCCCc1ccccc1)n1c2cccc(-c3ccccc3)c2oc1=O Show InChI InChI=1S/C24H22N2O3/c27-23(25-17-8-7-12-18-10-3-1-4-11-18)26-21-16-9-15-20(22(21)29-24(26)28)19-13-5-2-6-14-19/h1-6,9-11,13-16H,7-8,12,17H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec					Assay Description The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...				J Med Chem 50: 2767-78 (2007) BindingDB Entry DOI: 10.7270/Q23T9KH0
					More data for this Ligand-Target Pair