BDBM376840 US9920038, 1

SMILES: Cc1oc(C[C@H]2CCCCN2C(=O)c2ccccc2-n2nccn2)nc1C(C)(C)O

InChI Key: InChIKey=QLVFNJKLVRIPQN-MRXNPFEDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 376840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 1 (OX1) (Rattus norvegicus (Rat))	BDBM376840 (US9920038, 1) Show SMILES Cc1oc(C[C@H]2CCCCN2C(=O)c2ccccc2-n2nccn2)nc1C(C)(C)O Show InChI InChI=1S/C22H27N5O3/c1-15-20(22(2,3)29)25-19(30-15)14-16-8-6-7-13-26(16)21(28)17-9-4-5-10-18(17)27-23-11-12-24-27/h4-5,9-12,16,29H,6-8,13-14H2,1-3H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q2VQ350T
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM376840 (US9920038, 1) Show SMILES Cc1oc(C[C@H]2CCCCN2C(=O)c2ccccc2-n2nccn2)nc1C(C)(C)O Show InChI InChI=1S/C22H27N5O3/c1-15-20(22(2,3)29)25-19(30-15)14-16-8-6-7-13-26(16)21(28)17-9-4-5-10-18(17)27-23-11-12-24-27/h4-5,9-12,16,29H,6-8,13-14H2,1-3H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q2VQ350T
					More data for this Ligand-Target Pair