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SMILES: CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1

InChI Key: InChIKey=QMWHJEKSDJPKNC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384567   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384567
PNG
(US10285982, Compound 30)
Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccc(F)cc1
Show InChI InChI=1S/C29H24FN7O/c1-16(2)9-27(38)34-20-10-18(13-31-14-20)24-12-23-26(15-33-24)36-37-28(23)25-11-22-21(7-8-32-29(22)35-25)17-3-5-19(30)6-4-17/h3-8,10-16H,9H2,1-2H3,(H,32,35)(H,34,38)(H,36,37)
UniProtKB/SwissProt

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US Patent
n/an/an/an/a 444n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair