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SMILES: c1c([nH]c2nccc(-c3cccnc3)c12)-c1n[nH]c2cnc(cc12)-c1cncnc1

InChI Key: InChIKey=CPBJHENIXZYGFT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384679   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384679
PNG
(US10285982, Compound 111)
Show SMILES c1c([nH]c2nccc(-c3cccnc3)c12)-c1n[nH]c2cnc(cc12)-c1cncnc1
Show InChI InChI=1S/C22H14N8/c1-2-13(8-23-4-1)15-3-5-26-22-16(15)6-19(28-22)21-17-7-18(14-9-24-12-25-10-14)27-11-20(17)29-30-21/h1-12H,(H,26,28)(H,29,30)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair