null
SMILES: O=C(Cc1ccccc1)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1
InChI Key: InChIKey=PZBYNHKLESPHNC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene Wnt-1 (Homo sapiens (human)) | BDBM384682 (US10285982, Compound 122) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Istanbul University | Assay Description Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit... | Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2J105G8 | |||||||||||
More data for this Ligand-Target Pair |