Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384682'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM384682 (US10285982, Compound 122) Show SMILES O=C(Cc1ccccc1)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C31H22N8O/c40-29(12-19-4-2-1-3-5-19)36-22-13-21(16-33-17-22)26-15-25-28(18-35-26)38-39-30(25)27-14-24-23(8-11-34-31(24)37-27)20-6-9-32-10-7-20/h1-11,13-18H,12H2,(H,34,37)(H,36,40)(H,38,39)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Istanbul University					Assay Description Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...				Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2J105G8
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