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SMILES: O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1)C1CCC1

InChI Key: InChIKey=MSYBEPSBIQOBGM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384684   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384684
PNG
(US10285982, Compound 133)
Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1ccncc1)C1CCC1
Show InChI InChI=1S/C28H22N8O/c37-28(17-2-1-3-17)33-19-10-18(13-30-14-19)23-12-22-25(15-32-23)35-36-26(22)24-11-21-20(6-9-31-27(21)34-24)16-4-7-29-8-5-16/h4-15,17H,1-3H2,(H,31,34)(H,33,37)(H,35,36)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair