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SMILES: CN(C)c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCN(C)CC1

InChI Key: InChIKey=XPAOSAVXRFVDST-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384693   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384693
PNG
(US10285982, Compound 231)
Show SMILES CN(C)c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)N1CCN(C)CC1
Show InChI InChI=1S/C25H27N9/c1-32(2)17-10-16(13-26-14-17)20-11-18-22(15-28-20)30-31-24(18)21-12-19-23(4-5-27-25(19)29-21)34-8-6-33(3)7-9-34/h4-5,10-15H,6-9H2,1-3H3,(H,27,29)(H,30,31)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair