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BDBM384723 US10285983, Compound 20

SMILES: Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CC2)c1

InChI Key: InChIKey=CCWFVHDJJBUOOM-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384723   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384723
PNG
(US10285983, Compound 20)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CC2)c1
Show InChI InChI=1S/C28H20FN7O/c29-19-3-1-2-16(8-19)21-6-7-31-26-22(21)11-24(34-26)25-23-10-18(13-32-27(23)36-35-25)17-9-20(14-30-12-17)33-28(37)15-4-5-15/h1-3,6-15H,4-5H2,(H,31,34)(H,33,37)(H,32,35,36)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair