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BDBM384724 US10285983, Compound 24

SMILES: Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(CNCc2ccccc2)c1

InChI Key: InChIKey=YAHTWXPBDBDLIT-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384724   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384724
PNG
(US10285983, Compound 24)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(CNCc2ccccc2)c1
Show InChI InChI=1S/C32H24FN7/c33-25-8-4-7-22(12-25)26-9-10-36-31-27(26)14-29(38-31)30-28-13-24(19-37-32(28)40-39-30)23-11-21(17-35-18-23)16-34-15-20-5-2-1-3-6-20/h1-14,17-19,34H,15-16H2,(H,36,38)(H,37,39,40)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair