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BDBM384741 US10285983, Compound 78

SMILES: Fc1ccccc1-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CCCC2)c1

InChI Key: InChIKey=POELLJOIBAUKRZ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384741   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384741
PNG
(US10285983, Compound 78)
Show SMILES Fc1ccccc1-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CCCC2)c1
Show InChI InChI=1S/C30H24FN7O/c31-25-8-4-3-7-22(25)21-9-10-33-28-23(21)13-26(36-28)27-24-12-19(15-34-29(24)38-37-27)18-11-20(16-32-14-18)35-30(39)17-5-1-2-6-17/h3-4,7-17H,1-2,5-6H2,(H,33,36)(H,35,39)(H,34,37,38)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair