BDBM384758 US10285983, Compound 140

SMILES: c1c([nH]c2nccc(-c3ccncc3)c12)-c1n[nH]c2ncc(cc12)-c1ccccn1

InChI Key: InChIKey=ZVDLRDPPAGRJIY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM384758 (US10285983, Compound 140) Show SMILES c1c([nH]c2nccc(-c3ccncc3)c12)-c1n[nH]c2ncc(cc12)-c1ccccn1 Show InChI InChI=1S/C23H15N7/c1-2-7-25-19(3-1)15-11-18-21(29-30-23(18)27-13-15)20-12-17-16(6-10-26-22(17)28-20)14-4-8-24-9-5-14/h1-13H,(H,26,28)(H,27,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Istanbul University					Assay Description SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...				Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2D79DQJ
					More data for this Ligand-Target Pair