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BDBM384766 US10285983, Compound 247

SMILES: CN1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CCCCC2)c1

InChI Key: InChIKey=BJRPWKHKJPQWTE-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384766   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384766
PNG
(US10285983, Compound 247)
Show SMILES CN1CCN(CC1)c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CCCCC2)c1
Show InChI InChI=1S/C30H33N9O/c1-38-9-11-39(12-10-38)26-7-8-32-28-23(26)15-25(35-28)27-24-14-21(17-33-29(24)37-36-27)20-13-22(18-31-16-20)34-30(40)19-5-3-2-4-6-19/h7-8,13-19H,2-6,9-12H2,1H3,(H,32,35)(H,34,40)(H,33,36,37)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair