BDBM384767 US10285983, Compound 256

SMILES: c1c([nH]c2ncccc12)-c1n[nH]c2ncc(cc12)-c1cccnc1

InChI Key: InChIKey=QWJGMFYJPDCQDL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM384767 (US10285983, Compound 256) Show SMILES c1c([nH]c2ncccc12)-c1n[nH]c2ncc(cc12)-c1cccnc1 Show InChI InChI=1S/C18H12N6/c1-4-12(9-19-5-1)13-7-14-16(23-24-18(14)21-10-13)15-8-11-3-2-6-20-17(11)22-15/h1-10H,(H,20,22)(H,21,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
Istanbul University					Assay Description SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...				Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2D79DQJ
					More data for this Ligand-Target Pair