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BDBM384768 US10285983, Compound 263

SMILES: O=C(Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4cccnc4[nH]3)c2c1)c1ccccc1

InChI Key: InChIKey=AFBARBOQEJYQMP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384768   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384768
PNG
(US10285983, Compound 263)
Show SMILES O=C(Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4cccnc4[nH]3)c2c1)c1ccccc1
Show InChI InChI=1S/C25H17N7O/c33-25(15-5-2-1-3-6-15)29-19-9-17(12-26-14-19)18-10-20-22(31-32-24(20)28-13-18)21-11-16-7-4-8-27-23(16)30-21/h1-14H,(H,27,30)(H,29,33)(H,28,31,32)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair