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BDBM384774 US10285983, Compound 324

SMILES: CC(C)(C)CC(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccoc3)c2c1

InChI Key: InChIKey=ZKXYJXPPQJPXJE-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384774   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384774
PNG
(US10285983, Compound 324)
Show SMILES CC(C)(C)CC(=O)Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccoc3)c2c1
Show InChI InChI=1S/C28H25N7O2/c1-28(2,3)11-24(36)32-19-8-17(12-29-14-19)18-9-22-25(34-35-27(22)31-13-18)23-10-21-20(16-5-7-37-15-16)4-6-30-26(21)33-23/h4-10,12-15H,11H2,1-3H3,(H,30,33)(H,32,36)(H,31,34,35)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair