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BDBM384779 US10285983, Compound 518

SMILES: Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(OCc2ccccc2)c1

InChI Key: InChIKey=UTYZSSHSQFNSAD-UHFFFAOYSA-N

Data: 1 EC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384779   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384779
PNG
(US10285983, Compound 518)
Show SMILES Fc1cccc(c1)-c1ccnc2[nH]c(cc12)-c1n[nH]c2ncc(cc12)-c1cncc(OCc2ccccc2)c1
Show InChI InChI=1S/C31H21FN6O/c32-23-8-4-7-20(11-23)25-9-10-34-30-26(25)14-28(36-30)29-27-13-22(16-35-31(27)38-37-29)21-12-24(17-33-15-21)39-18-19-5-2-1-3-6-19/h1-17H,18H2,(H,34,36)(H,35,37,38)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair