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BDBM384780 US10285983, Compound 533

SMILES: Oc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccc(F)cc3)c2c1

InChI Key: InChIKey=KEUJOGNWQQGPMN-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384780   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384780
PNG
(US10285983, Compound 533)
Show SMILES Oc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccc(F)cc3)c2c1
Show InChI InChI=1S/C24H15FN6O/c25-16-3-1-13(2-4-16)18-5-6-27-23-19(18)9-21(29-23)22-20-8-15(11-28-24(20)31-30-22)14-7-17(32)12-26-10-14/h1-12,32H,(H,27,29)(H,28,30,31)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair