BindingDB logo
myBDB logout

BDBM384782 US10285983, Compound 577

SMILES: O=C(CC1CCNCC1)Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccncc3)c2c1

InChI Key: InChIKey=WHLAZKIHWROTRW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384782   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384782
PNG
(US10285983, Compound 577)
Show SMILES O=C(CC1CCNCC1)Nc1cncc(c1)-c1cnc2[nH]nc(-c3cc4c(ccnc4[nH]3)-c3ccncc3)c2c1
Show InChI InChI=1S/C30H27N9O/c40-27(11-18-1-6-31-7-2-18)36-22-12-20(15-33-17-22)21-13-25-28(38-39-30(25)35-16-21)26-14-24-23(5-10-34-29(24)37-26)19-3-8-32-9-4-19/h3-5,8-10,12-18,31H,1-2,6-7,11H2,(H,34,37)(H,36,40)(H,35,38,39)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>1.00E+4n/an/an/an/a



Istanbul University



Assay Description
SW480 colon carcinoma cells were transduced with a lentiviral vector expressing luciferase with a human Sp5 promoter consisting of a sequence of eigh...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2D79DQJ
More data for this
Ligand-Target Pair