BDBM39152 3-(4-benzylpiperazin-1-yl)-4-chloro-1-(3,4-dichlorophenyl)pyrrole-2,5-dione::3-(4-benzylpiperazino)-4-chloro-1-(3,4-dichlorophenyl)-3-pyrroline-2,5-quinone::3-chloranyl-1-(3,4-dichlorophenyl)-4-[4-(phenylmethyl)piperazin-1-yl]pyrrole-2,5-dione::3-chloro-1-(3,4-dichlorophenyl)-4-(4-benzylpiperazin-1-yl)-1H-pyrrole-2,5-dione::3-chloro-1-(3,4-dichlorophenyl)-4-[4-(phenylmethyl)-1-piperazinyl]pyrrole-2,5-dione::CHEMBL1272313::MLS-0090866.0001::cid_16654662

SMILES: ClC1=C(N2CCN(Cc3ccccc3)CC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=SBNOUSIFZCQQID-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 39152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bfl-1 (Mus musculus (Mouse))	BDBM39152 (3-(4-benzylpiperazin-1-yl)-4-chloro-1-(3,4-dichlor...) Show SMILES ClC1=C(N2CCN(Cc3ccccc3)CC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:1| Show InChI InChI=1S/C21H18Cl3N3O2/c22-16-7-6-15(12-17(16)23)27-20(28)18(24)19(21(27)29)26-10-8-25(9-11-26)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2X065GM
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM39152 (3-(4-benzylpiperazin-1-yl)-4-chloro-1-(3,4-dichlor...) Show SMILES ClC1=C(N2CCN(Cc3ccccc3)CC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:1| Show InChI InChI=1S/C21H18Cl3N3O2/c22-16-7-6-15(12-17(16)23)27-20(28)18(24)19(21(27)29)26-10-8-25(9-11-26)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assay				Bioorg Med Chem Lett 20: 6560-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.046 BindingDB Entry DOI: 10.7270/Q27D2VCZ
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM39152 (3-(4-benzylpiperazin-1-yl)-4-chloro-1-(3,4-dichlor...) Show SMILES ClC1=C(N2CCN(Cc3ccccc3)CC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:1| Show InChI InChI=1S/C21H18Cl3N3O2/c22-16-7-6-15(12-17(16)23)27-20(28)18(24)19(21(27)29)26-10-8-25(9-11-26)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assay				Bioorg Med Chem Lett 20: 6560-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.046 BindingDB Entry DOI: 10.7270/Q27D2VCZ
					More data for this Ligand-Target Pair
Bfl-1 (Mus musculus (Mouse))	BDBM39152 (3-(4-benzylpiperazin-1-yl)-4-chloro-1-(3,4-dichlor...) Show SMILES ClC1=C(N2CCN(Cc3ccccc3)CC2)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:1| Show InChI InChI=1S/C21H18Cl3N3O2/c22-16-7-6-15(12-17(16)23)27-20(28)18(24)19(21(27)29)26-10-8-25(9-11-26)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2K072NW
					More data for this Ligand-Target Pair