null

SMILES: CCOc1ccccc1C(=O)N1C[C@@H](CC[C@H]1C)n1ncc(n1)C(C)(C)O

InChI Key: InChIKey=NHDHGTRMHMUSIA-HUUCEWRRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM401795 ((2-Ethoxyphenyl)((2R,5R)-5-(4-(2-hydroxypropan-2-y...) Show SMILES CCOc1ccccc1C(=O)N1C[C@@H](CC[C@H]1C)n1ncc(n1)C(C)(C)O Show InChI InChI=1S/C20H28N4O3/c1-5-27-17-9-7-6-8-16(17)19(25)23-13-15(11-10-14(23)2)24-21-12-18(22-24)20(3,4)26/h6-9,12,14-15,26H,5,10-11,13H2,1-4H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM401795 ((2-Ethoxyphenyl)((2R,5R)-5-(4-(2-hydroxypropan-2-y...) Show SMILES CCOc1ccccc1C(=O)N1C[C@@H](CC[C@H]1C)n1ncc(n1)C(C)(C)O Show InChI InChI=1S/C20H28N4O3/c1-5-27-17-9-7-6-8-16(17)19(25)23-13-15(11-10-14(23)2)24-21-12-18(22-24)20(3,4)26/h6-9,12,14-15,26H,5,10-11,13H2,1-4H3/t14-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair