null

SMILES: C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1OC(F)F)n1ncc(n1)C(C)(C)O

InChI Key: InChIKey=ZXLQWYCDVHCCRV-CHWSQXEVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM401804 ((2-(Difluoromethoxy)phenyl)((2R,5R)-5-(4-(2-hydrox...) Show SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1OC(F)F)n1ncc(n1)C(C)(C)O Show InChI InChI=1S/C19H24F2N4O3/c1-12-8-9-13(25-22-10-16(23-25)19(2,3)27)11-24(12)17(26)14-6-4-5-7-15(14)28-18(20)21/h4-7,10,12-13,18,27H,8-9,11H2,1-3H3/t12-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM401804 ((2-(Difluoromethoxy)phenyl)((2R,5R)-5-(4-(2-hydrox...) Show SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1OC(F)F)n1ncc(n1)C(C)(C)O Show InChI InChI=1S/C19H24F2N4O3/c1-12-8-9-13(25-22-10-16(23-25)19(2,3)27)11-24(12)17(26)14-6-4-5-7-15(14)28-18(20)21/h4-7,10,12-13,18,27H,8-9,11H2,1-3H3/t12-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair