null

SMILES: CCOc1ncccc1C(=O)N1C[C@@H](CC[C@H]1C)n1nc(C)c(n1)C(C)(C)O

InChI Key: InChIKey=BKFYTWSPBVTMOW-UKRRQHHQSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 401849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM401849 (2-(2-{(3R,6R)-1-[(2- Ethoxypyridin-3-yl)carbonyl]-...) Show SMILES CCOc1ncccc1C(=O)N1C[C@@H](CC[C@H]1C)n1nc(C)c(n1)C(C)(C)O |r| Show InChI InChI=1S/C20H29N5O3/c1-6-28-18-16(8-7-11-21-18)19(26)24-12-15(10-9-13(24)2)25-22-14(3)17(23-25)20(4,5)27/h7-8,11,13,15,27H,6,9-10,12H2,1-5H3/t13-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM401849 (2-(2-{(3R,6R)-1-[(2- Ethoxypyridin-3-yl)carbonyl]-...) Show SMILES CCOc1ncccc1C(=O)N1C[C@@H](CC[C@H]1C)n1nc(C)c(n1)C(C)(C)O |r| Show InChI InChI=1S/C20H29N5O3/c1-6-28-18-16(8-7-11-21-18)19(26)24-12-15(10-9-13(24)2)25-22-14(3)17(23-25)20(4,5)27/h7-8,11,13,15,27H,6,9-10,12H2,1-5H3/t13-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.1	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester					Assay Description For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...				J Med Chem 52: 7142-56 (2009) BindingDB Entry DOI: 10.7270/Q2S75JPN
					More data for this Ligand-Target Pair