null
SMILES: CCOC(=O)c1cc2C(=O)c3ccccc3-n2c1N
InChI Key: InChIKey=NLOFNKPOURZRLR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM41787 (1-amino-4-keto-pyrrol[1,2-a]indole-2-carboxylic ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2Z036KJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM41787 (1-amino-4-keto-pyrrol[1,2-a]indole-2-carboxylic ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.99E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2T72FVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tropomyosin alpha-1 chain (Sus scrofa) | BDBM41787 (1-amino-4-keto-pyrrol[1,2-a]indole-2-carboxylic ac...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 2.44E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21N7ZKB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycoprotein 42 (Human herpesvirus 4 type 2) | BDBM41787 (1-amino-4-keto-pyrrol[1,2-a]indole-2-carboxylic ac...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human)) | BDBM41787 (1-amino-4-keto-pyrrol[1,2-a]indole-2-carboxylic ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2N58JS6 | |||||||||||
More data for this Ligand-Target Pair |