BDBM426634 US10544075, Compound JD-20

SMILES: CC(C)c1cc(Cc2c(Br)cc(OCC(O)=O)cc2Br)ccc1O

InChI Key: InChIKey=PKCVPDWHPSTUAV-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM426634 (US10544075, Compound JD-20) Show SMILES CC(C)c1cc(Cc2c(Br)cc(OCC(O)=O)cc2Br)ccc1O Show InChI InChI=1S/C18H18Br2O4/c1-10(2)13-5-11(3-4-17(13)21)6-14-15(19)7-12(8-16(14)20)24-9-18(22)23/h3-5,7-8,10,21H,6,9H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.880	n/a	n/a	n/a	n/a
OREGON HEALTH & SCIENCE UNIVERSITY US Patent					Assay Description Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...				US Patent US10544075 (2020) BindingDB Entry DOI: 10.7270/Q2NP26SZ
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM426634 (US10544075, Compound JD-20) Show SMILES CC(C)c1cc(Cc2c(Br)cc(OCC(O)=O)cc2Br)ccc1O Show InChI InChI=1S/C18H18Br2O4/c1-10(2)13-5-11(3-4-17(13)21)6-14-15(19)7-12(8-16(14)20)24-9-18(22)23/h3-5,7-8,10,21H,6,9H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.96	n/a	n/a	n/a	n/a
OREGON HEALTH & SCIENCE UNIVERSITY US Patent					Assay Description Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...				US Patent US10544075 (2020) BindingDB Entry DOI: 10.7270/Q2NP26SZ
					More data for this Ligand-Target Pair