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SMILES: CCn1ncc2c(cnnc12)-c1ccc(F)c(c1)-c1cc2CN(C)C(=O)c2cc1OC

InChI Key: InChIKey=GIWBVYFKNZTXDT-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430027   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-2


(Homo sapiens (Human))		BDBM430027
PNG
(5-[5-(1-Ethyl-1H-pyrazolo[3,4-c]pyridazin-4-yl)-2-...)
Show SMILES CCn1ncc2c(cnnc12)-c1ccc(F)c(c1)-c1cc2CN(C)C(=O)c2cc1OC
Show InChI InChI=1S/C23H20FN5O2/c1-4-29-22-19(11-26-29)18(10-25-27-22)13-5-6-20(24)16(7-13)17-8-14-12-28(2)23(30)15(14)9-21(17)31-3/h5-11H,4,12H2,1-3H3
PDB

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US Patent
 11.8n/an/an/an/an/an/an/an/a



PFIZER LIMITED

US Patent


Assay Description
The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...

US Patent US10538523 (2020)


BindingDB Entry DOI: 10.7270/Q2RB771W
More data for this
Ligand-Target Pair