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SMILES: COc1cc2ncnc3Nc4c5OCOc5ccc4CN(CCCCCOc1cc23)C(=O)OCc1ccccc1

InChI Key: InChIKey=RISYBLQATJHOMR-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446703   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Fyn


(Homo sapiens (Human))		BDBM446703
PNG
(US10688093, Compound B50 (U.S. Pat. No.-8,492,377)...)
Show SMILES COc1cc2ncnc3Nc4c5OCOc5ccc4CN(CCCCCOc1cc23)C(=O)OCc1ccccc1
Show InChI InChI=1S/C30H30N4O6/c1-36-25-15-23-22-14-26(25)37-13-7-3-6-12-34(30(35)38-17-20-8-4-2-5-9-20)16-21-10-11-24-28(40-19-39-24)27(21)33-29(22)32-18-31-23/h2,4-5,8-11,14-15,18H,3,6-7,12-13,16-17,19H2,1H3,(H,31,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.69n/an/an/an/an/an/a



TBA

US Patent


Assay Description
The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...

US Patent US10688093 (2020)

More data for this
Ligand-Target Pair