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SMILES: COc1ccc2CCc3cnc(Nc4cc(C)c(OCCN(C)C)c(C)c4)nc3-c2c1

InChI Key: InChIKey=SNPGFHSXAGWITE-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446705   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Fyn


(Homo sapiens (Human))		BDBM446705
PNG
(N-{4-[2-(dimethyl- amino)ethoxy]- 3,5-dimethyl phe...)
Show SMILES COc1ccc2CCc3cnc(Nc4cc(C)c(OCCN(C)C)c(C)c4)nc3-c2c1
Show InChI InChI=1S/C25H30N4O2/c1-16-12-20(13-17(2)24(16)31-11-10-29(3)4)27-25-26-15-19-7-6-18-8-9-21(30-5)14-22(18)23(19)28-25/h8-9,12-15H,6-7,10-11H2,1-5H3,(H,26,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
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UniChem
US Patent
n/an/a 8n/an/an/an/an/an/a



TBA

US Patent


Assay Description
The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...

US Patent US10688093 (2020)

More data for this
Ligand-Target Pair