Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Fyn' and Ligand = 'BDBM446705'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM446705 (N-{4-[2-(dimethyl- amino)ethoxy]- 3,5-dimethyl phe...) Show SMILES COc1ccc2CCc3cnc(Nc4cc(C)c(OCCN(C)C)c(C)c4)nc3-c2c1 Show InChI InChI=1S/C25H30N4O2/c1-16-12-20(13-17(2)24(16)31-11-10-29(3)4)27-25-26-15-19-7-6-18-8-9-21(30-5)14-22(18)23(19)28-25/h8-9,12-15H,6-7,10-11H2,1-5H3,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...				US Patent US10688093 (2020) BindingDB Entry DOI: 10.7270/Q2Q81H48
					More data for this Ligand-Target Pair