null
SMILES: CC1C[C@@H](NC(=O)Nc2ccc(Cl)cc2F)C(=O)N1c1ccc(c(F)c1F)-c1cccnc1P(C)(C)=O
InChI Key: InChIKey=AYDOUEBSXOSSGX-GAGCMDECSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-formyl peptide receptor 2 (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki... | US Patent US10676431 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
fMet-Leu-Phe receptor (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki... | US Patent US10676431 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-formyl peptide receptor 2 (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.810 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki... | US Patent US10676431 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
fMet-Leu-Phe receptor (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | n/a | n/a | 610 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-formyl peptide receptor 2 (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
fMet-Leu-Phe receptor (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-formyl peptide receptor 2 (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | n/a | n/a | 0.810 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
fMet-Leu-Phe receptor (Homo sapiens (Human)) | BDBM450358 (US10676431, Example 121 | US10676431, Example 122 ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 610 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki... | US Patent US10676431 (2020) | |||||||||||
More data for this Ligand-Target Pair |