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SMILES: Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cc(cnc1F)[N+]([O-])=O

InChI Key: InChIKey=DQAFQEGGRBEJNZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 451733   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 4 (Homo sapiens (Human))	BDBM451733 (6-(6-amino-2'-fluoro-5'-nitro- [3,3'-bipyridin]-5-...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cc(cnc1F)[N+]([O-])=O Show InChI InChI=1S/C19H14FN5O3/c20-17-15(7-13(9-23-17)25(27)28)12-6-16(18(21)24-8-12)10-1-2-14-11(5-10)3-4-22-19(14)26/h1-2,5-9H,3-4H2,(H2,21,24)(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 26 (Homo sapiens (Human))	BDBM451733 (6-(6-amino-2'-fluoro-5'-nitro- [3,3'-bipyridin]-5-...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cc(cnc1F)[N+]([O-])=O Show InChI InChI=1S/C19H14FN5O3/c20-17-15(7-13(9-23-17)25(27)28)12-6-16(18(21)24-8-12)10-1-2-14-11(5-10)3-4-22-19(14)26/h1-2,5-9H,3-4H2,(H2,21,24)(H,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 24 (Homo sapiens (Human))	BDBM451733 (6-(6-amino-2'-fluoro-5'-nitro- [3,3'-bipyridin]-5-...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cc(cnc1F)[N+]([O-])=O Show InChI InChI=1S/C19H14FN5O3/c20-17-15(7-13(9-23-17)25(27)28)12-6-16(18(21)24-8-12)10-1-2-14-11(5-10)3-4-22-19(14)26/h1-2,5-9H,3-4H2,(H2,21,24)(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM451733 (6-(6-amino-2'-fluoro-5'-nitro- [3,3'-bipyridin]-5-...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1cc(cnc1F)[N+]([O-])=O Show InChI InChI=1S/C19H14FN5O3/c20-17-15(7-13(9-23-17)25(27)28)12-6-16(18(21)24-8-12)10-1-2-14-11(5-10)3-4-22-19(14)26/h1-2,5-9H,3-4H2,(H2,21,24)(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020)
					More data for this Ligand-Target Pair