BDBM46273 2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-ylamino)-4-oxidanylidene-1,3-thiazol-5-ylidene]methyl]phenoxy]ethanoic acid::2-[2-chloro-6-ethoxy-4-[(E)-[2-(2-naphthalenylamino)-4-oxo-5-thiazolylidene]methyl]phenoxy]acetic acid::2-[2-chloro-6-ethoxy-4-[(E)-[2-(naphthalen-2-ylamino)-4-oxo-1,3-thiazol-5-ylidene]methyl]phenoxy]acetic acid::2-[2-chloro-6-ethoxy-4-[(E)-[4-keto-2-(2-naphthylamino)-2-thiazolin-5-ylidene]methyl]phenoxy]acetic acid::MLS-0425588.0001::cid_1228861

SMILES: CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O

InChI Key: InChIKey=ACGNBGCZLANJSP-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 46273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46273 (2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-yl...) Show SMILES CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O |w:6.5,c:22| Show InChI InChI=1S/C24H19ClN2O5S/c1-2-31-19-10-14(9-18(25)22(19)32-13-21(28)29)11-20-23(30)27-24(33-20)26-17-8-7-15-5-3-4-6-16(15)12-17/h3-12H,2,13H2,1H3,(H,28,29)(H,26,27,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2474894
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46273 (2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-yl...) Show SMILES CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O |w:6.5,c:22| Show InChI InChI=1S/C24H19ClN2O5S/c1-2-31-19-10-14(9-18(25)22(19)32-13-21(28)29)11-20-23(30)27-24(33-20)26-17-8-7-15-5-3-4-6-16(15)12-17/h3-12H,2,13H2,1H3,(H,28,29)(H,26,27,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	373	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21N7ZJW
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 12 isoform 2 (Homo sapiens (Human))	BDBM46273 (2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-yl...) Show SMILES CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O |w:6.5,c:22| Show InChI InChI=1S/C24H19ClN2O5S/c1-2-31-19-10-14(9-18(25)22(19)32-13-21(28)29)11-20-23(30)27-24(33-20)26-17-8-7-15-5-3-4-6-16(15)12-17/h3-12H,2,13H2,1H3,(H,28,29)(H,26,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q28G8J5T
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM46273 (2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-yl...) Show SMILES CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O |w:6.5,c:22| Show InChI InChI=1S/C24H19ClN2O5S/c1-2-31-19-10-14(9-18(25)22(19)32-13-21(28)29)11-20-23(30)27-24(33-20)26-17-8-7-15-5-3-4-6-16(15)12-17/h3-12H,2,13H2,1H3,(H,28,29)(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M9073J
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46273 (2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-yl...) Show SMILES CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O |w:6.5,c:22| Show InChI InChI=1S/C24H19ClN2O5S/c1-2-31-19-10-14(9-18(25)22(19)32-13-21(28)29)11-20-23(30)27-24(33-20)26-17-8-7-15-5-3-4-6-16(15)12-17/h3-12H,2,13H2,1H3,(H,28,29)(H,26,27,30)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	466	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BR8QNJ
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM46273 (2-[2-chloranyl-6-ethoxy-4-[(E)-[2-(naphthalen-2-yl...) Show SMILES CCOc1cc(C=C2SC(Nc3ccc4ccccc4c3)=NC2=O)cc(Cl)c1OCC(O)=O |w:6.5,c:22| Show InChI InChI=1S/C24H19ClN2O5S/c1-2-31-19-10-14(9-18(25)22(19)32-13-21(28)29)11-20-23(30)27-24(33-20)26-17-8-7-15-5-3-4-6-16(15)12-17/h3-12H,2,13H2,1H3,(H,28,29)(H,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QZ28FP
					More data for this Ligand-Target Pair