null

SMILES: C[C@@H]1CS(=O)(=O)NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@H]4[C@](O)(CN4CCN5CCCC[C@@H]5C4)\C=C\[C@@H]1C)c3c2

InChI Key: InChIKey=ZAANKZNOCXZFPS-WMIVWLHWSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 470777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human))	BDBM470777 ((1S,3'R,6'R,7'S,8'E,10'S,11'S)- 6-chloro-7'-((9aS)...) Show SMILES C[C@@H]1CS(=O)(=O)NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@H]4[C@](O)(CN4CCN5CCCC[C@@H]5C4)\C=C\[C@@H]1C)c3c2 |r,t:51| Show InChI InChI=1S/C41H55ClN4O5S/c1-28-14-16-41(48,26-44-18-19-45-17-4-3-7-34(45)23-44)36-11-8-32(36)22-46-25-40(15-5-6-30-20-33(42)10-12-35(30)40)27-51-38-13-9-31(21-37(38)46)39(47)43-52(49,50)24-29(28)2/h9-10,12-14,16,20-21,28-29,32,34,36,48H,3-8,11,15,17-19,22-27H2,1-2H3,(H,43,47)/b16-14+/t28-,29+,32-,34+,36+,40-,41+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.0470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327] (Homo sapiens (Human))	BDBM470777 ((1S,3'R,6'R,7'S,8'E,10'S,11'S)- 6-chloro-7'-((9aS)...) Show SMILES C[C@@H]1CS(=O)(=O)NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]4CC[C@H]4[C@](O)(CN4CCN5CCCC[C@@H]5C4)\C=C\[C@@H]1C)c3c2 |r,t:51| Show InChI InChI=1S/C41H55ClN4O5S/c1-28-14-16-41(48,26-44-18-19-45-17-4-3-7-34(45)23-44)36-11-8-32(36)22-46-25-40(15-5-6-30-20-33(42)10-12-35(30)40)27-51-38-13-9-31(21-37(38)46)39(47)43-52(49,50)24-29(28)2/h9-10,12-14,16,20-21,28-29,32,34,36,48H,3-8,11,15,17-19,22-27H2,1-2H3,(H,43,47)/b16-14+/t28-,29+,32-,34+,36+,40-,41+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0470	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...				US Patent US10821115 (2020)
					More data for this Ligand-Target Pair