null
SMILES: CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCC(N)(CC)CC2)n1
InChI Key: InChIKey=HBALAPRVSOJBQZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Activin receptor type-1 (Homo sapiens (Human)) | BDBM488104 (N-(4-(4-Amino-4- ethylpiperidin-1- yl)phenyl)-4-(1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN; THE UNIVERSITY OF TOKYO US Patent | Assay Description TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol... | US Patent US10954216 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Activin receptor type-1 [R206H] (Homo sapiens (Human)) | BDBM488104 (N-(4-(4-Amino-4- ethylpiperidin-1- yl)phenyl)-4-(1...) | PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN; THE UNIVERSITY OF TOKYO US Patent | Assay Description R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe... | US Patent US10954216 (2021) | |||||||||||
More data for this Ligand-Target Pair |