Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM488104'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activin receptor type-1 (Homo sapiens (Human))	BDBM488104 (N-(4-(4-Amino-4- ethylpiperidin-1- yl)phenyl)-4-(1...) Show SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCC(N)(CC)CC2)n1 Show InChI InChI=1S/C27H32N8/c1-3-27(28)12-16-34(17-13-27)22-9-7-21(8-10-22)31-26-30-15-11-24(32-26)23-19-35(4-2)33-25(23)20-6-5-14-29-18-20/h5-11,14-15,18-19H,3-4,12-13,16-17,28H2,1-2H3,(H,30,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
RIKEN; THE UNIVERSITY OF TOKYO US Patent					Assay Description TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...				US Patent US10954216 (2021) BindingDB Entry DOI: 10.7270/Q2P84G0W
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