BDBM49423 (E)-3-(3,4-dimethylanilino)-2-(3-thienyl)acrylonitrile::(E)-3-(3,4-dimethylanilino)-2-(3-thiophenyl)-2-propenenitrile::(E)-3-(3,4-dimethylanilino)-2-thiophen-3-ylprop-2-enenitrile::(E)-3-[(3,4-dimethylphenyl)amino]-2-thiophen-3-yl-prop-2-enenitrile::MLS000539447::SMR000125105::cid_2766393

SMILES: Cc1ccc(cc1C)N=CC(C#N)c1ccsc1

InChI Key: InChIKey=NNVITGHWPHCCAR-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 49423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM49423 ((E)-3-(3,4-dimethylanilino)-2-(3-thienyl)acrylonit...) Show SMILES Cc1ccc(cc1C)N=CC(C#N)c1ccsc1 |w:8.8| Show InChI InChI=1S/C15H14N2S/c1-11-3-4-15(7-12(11)2)17-9-14(8-16)13-5-6-18-10-13/h3-7,9-10,14H,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	6.75E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...				PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2ZP44SP
					More data for this Ligand-Target Pair
Nuclear factor NF-kappa-B (Homo sapiens (Human))	BDBM49423 ((E)-3-(3,4-dimethylanilino)-2-(3-thienyl)acrylonit...) Show SMILES Cc1ccc(cc1C)N=CC(C#N)c1ccsc1 |w:8.8| Show InChI InChI=1S/C15H14N2S/c1-11-3-4-15(7-12(11)2)17-9-14(8-16)13-5-6-18-10-13/h3-7,9-10,14H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	6.87E+3	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27P8WT7
					More data for this Ligand-Target Pair