BDBM50003369 1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine::1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine; oxalic acid::1-methyl-5-(4-propoxy-1,2,5-thiadiazol-3-yl)-1,2,3,6-tetrahydropyridine::CHEMBL303922::CHEMBL308803

SMILES: CCCOc1nsnc1C1=CCCN(C)C1

InChI Key: InChIKey=VGRPVZDIAOGCMM-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50003369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against rat hippocampus Muscarinic acetylcholine receptor M1 using [3H]-pirenzepine (Pz) as radioligand				J Med Chem 35: 4011-9 (1992) BindingDB Entry DOI: 10.7270/Q2KW5F1K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]-pirenzepine in rat cerebral cortical membranes				Bioorg Med Chem Lett 4: 2205-2210 (1994) Article DOI: 10.1016/S0960-894X(00)80072-4 BindingDB Entry DOI: 10.7270/Q2T72HCC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells in continuous presence of radioligand				Bioorg Med Chem 16: 1376-92 (2008) Article DOI: 10.1016/j.bmc.2007.10.058 BindingDB Entry DOI: 10.7270/Q2CR5VNC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against rat hippocampus Muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) as radioligand				J Med Chem 35: 4011-9 (1992) BindingDB Entry DOI: 10.7270/Q2KW5F1K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]-pirenzepine in rat cerebral cortical membranes				Bioorg Med Chem Lett 4: 2205-2210 (1994) Article DOI: 10.1016/S0960-894X(00)80072-4 BindingDB Entry DOI: 10.7270/Q2T72HCC
					More data for this Ligand-Target Pair