BDBM50005681 2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylamino-propyl ester::CHEMBL286008

SMILES: CN(C)CCCOC(=O)C(C)(C1CCCCC1)c1ccccc1

InChI Key: InChIKey=HPHMHCRNJVKYKE-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50005681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50005681 (2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...) Show SMILES CN(C)CCCOC(=O)C(C)(C1CCCCC1)c1ccccc1 Show InChI InChI=1S/C20H31NO2/c1-20(17-11-6-4-7-12-17,18-13-8-5-9-14-18)19(22)23-16-10-15-21(2)3/h4,6-7,11-12,18H,5,8-10,13-16H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...				J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50005681 (2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...) Show SMILES CN(C)CCCOC(=O)C(C)(C1CCCCC1)c1ccccc1 Show InChI InChI=1S/C20H31NO2/c1-20(17-11-6-4-7-12-17,18-13-8-5-9-14-18)19(22)23-16-10-15-21(2)3/h4,6-7,11-12,18H,5,8-10,13-16H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...				J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50005681 (2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...) Show SMILES CN(C)CCCOC(=O)C(C)(C1CCCCC1)c1ccccc1 Show InChI InChI=1S/C20H31NO2/c1-20(17-11-6-4-7-12-17,18-13-8-5-9-14-18)19(22)23-16-10-15-21(2)3/h4,6-7,11-12,18H,5,8-10,13-16H2,1-3H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...				J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50005681 (2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...) Show SMILES CN(C)CCCOC(=O)C(C)(C1CCCCC1)c1ccccc1 Show InChI InChI=1S/C20H31NO2/c1-20(17-11-6-4-7-12-17,18-13-8-5-9-14-18)19(22)23-16-10-15-21(2)3/h4,6-7,11-12,18H,5,8-10,13-16H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Antimuscurinic potency and subset specificity of the compound was characterised by its inhibition of the [3H]-NMS Binding to Muscarinic acetylcholine...				J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0
					More data for this Ligand-Target Pair
Pancreatic alpha-amylase (Rattus norvegicus)	BDBM50005681 (2-Cyclohexyl-2-phenyl-propionic acid 3-dimethylami...) Show SMILES CN(C)CCCOC(=O)C(C)(C1CCCCC1)c1ccccc1 Show InChI InChI=1S/C20H31NO2/c1-20(17-11-6-4-7-12-17,18-13-8-5-9-14-18)19(22)23-16-10-15-21(2)3/h4,6-7,11-12,18H,5,8-10,13-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Inhibition of the release of Alpha-amylase from rat pancreatic acinar cells.				J Med Chem 35: 1290-5 (1992) BindingDB Entry DOI: 10.7270/Q28914T0
					More data for this Ligand-Target Pair