BDBM50006551 (+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-dione::(-)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-dione::3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-dione::CHEMBL70901

SMILES: Nc1ccc(cc1)C1(CCC(=O)NC1=O)C1CCCCC1

InChI Key: InChIKey=NTKWRAAWKFNECW-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50006551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11A1 (CYP11A1) (Bos taurus (Bovine))	BDBM50006551 ((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...) Show SMILES Nc1ccc(cc1)C1(CCC(=O)NC1=O)C1CCCCC1 Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Inhibition of bovine adrenal desmolase				J Med Chem 35: 2210-4 (1992) BindingDB Entry DOI: 10.7270/Q26972HS
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50006551 ((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...) Show SMILES Nc1ccc(cc1)C1(CCC(=O)NC1=O)C1CCCCC1 Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Concentration of the compound inhibiting Aromatase				J Med Chem 35: 2210-4 (1992) BindingDB Entry DOI: 10.7270/Q26972HS
					More data for this Ligand-Target Pair
Cytochrome P450 11A1 (CYP11A1) (Bos taurus (Bovine))	BDBM50006551 ((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...) Show SMILES Nc1ccc(cc1)C1(CCC(=O)NC1=O)C1CCCCC1 Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Inhibition of bovine adrenal desmolase				J Med Chem 35: 2210-4 (1992) BindingDB Entry DOI: 10.7270/Q26972HS
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50006551 ((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...) Show SMILES Nc1ccc(cc1)C1(CCC(=O)NC1=O)C1CCCCC1 Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Inhibition of bovine adrenal desmolase				J Med Chem 35: 2210-4 (1992) BindingDB Entry DOI: 10.7270/Q26972HS
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50006551 ((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...) Show SMILES Nc1ccc(cc1)C1(CCC(=O)NC1=O)C1CCCCC1 Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Universität des Saarlandes Curated by ChEMBL					Assay Description Concentration of the compound inhibiting Aromatase				J Med Chem 35: 2210-4 (1992) BindingDB Entry DOI: 10.7270/Q26972HS
					More data for this Ligand-Target Pair
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50006551 ((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...) Show SMILES Nc1ccc(cc1)C1(CCC(=O)NC1=O)C1CCCCC1 Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of the Saarland Curated by ChEMBL					Assay Description Inhibition of thromboxane synthase P450 TXA2				J Med Chem 43: 4437-45 (2000) BindingDB Entry DOI: 10.7270/Q25H7FH3
					More data for this Ligand-Target Pair