BDBM50007410 1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine::CHEMBL112125

SMILES: Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1

InChI Key: InChIKey=NAFPAUNPTMADIM-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50007410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma opioid receptor (RAT)	BDBM50007410 (1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...) Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 23: 6920-6922 (2013) Article DOI: 10.1016/j.bmcl.2013.09.038 BindingDB Entry DOI: 10.7270/Q2J969B5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007410 (1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...) Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligand				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50007410 (1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...) Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	391	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 23: 6920-6922 (2013) Article DOI: 10.1016/j.bmcl.2013.09.038 BindingDB Entry DOI: 10.7270/Q2J969B5
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007410 (1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...) Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 23: 6920-6922 (2013) Article DOI: 10.1016/j.bmcl.2013.09.038 BindingDB Entry DOI: 10.7270/Q2J969B5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50007410 (1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...) Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 23: 6920-6922 (2013) Article DOI: 10.1016/j.bmcl.2013.09.038 BindingDB Entry DOI: 10.7270/Q2J969B5
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50007410 (1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...) Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 23: 6920-6922 (2013) Article DOI: 10.1016/j.bmcl.2013.09.038 BindingDB Entry DOI: 10.7270/Q2J969B5
					More data for this Ligand-Target Pair