new BindingDB logo
myBDB logout

BDBM50008511 CHEMBL3235571

SMILES: CCOc1ccc2nc(NC(=O)Cc3cc(OC)c(OC)c(OC)c3)sc2c1

InChI Key: InChIKey=LDVWMPDGWTZZKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008511   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase I isoform delta


(Homo sapiens (Human))
BDBM50008511
PNG
(CHEMBL3235571)
Show SMILES CCOc1ccc2nc(NC(=O)Cc3cc(OC)c(OC)c(OC)c3)sc2c1
Show InChI InChI=1S/C20H22N2O5S/c1-5-27-13-6-7-14-17(11-13)28-20(21-14)22-18(23)10-12-8-15(24-2)19(26-4)16(9-12)25-3/h6-9,11H,5,10H2,1-4H3,(H,21,22,23)
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.43E+3n/an/an/an/an/an/a



CSIC

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay


J Med Chem 57: 2755-72 (2014)


Article DOI: 10.1021/jm500065f
BindingDB Entry DOI: 10.7270/Q21N82NV
More data for this
Ligand-Target Pair